I Domains in Integrins Donald Gullberg

ISBN:

Published: August 31st 2003

Kindle Edition

186 pages


Description

I Domains in Integrins  by  Donald Gullberg

I Domains in Integrins by Donald Gullberg
August 31st 2003 | Kindle Edition | PDF, EPUB, FB2, DjVu, talking book, mp3, ZIP | 186 pages | ISBN: | 4.30 Mb

In vertebrates, the integrin family includes 24 members. As the alpha-chains were sequenced, some were observed to have an inserted domain similar to the A domain in several matrix and complement proteins. This inserted ligand binding domain isMoreIn vertebrates, the integrin family includes 24 members. As the alpha-chains were sequenced, some were observed to have an inserted domain similar to the A domain in several matrix and complement proteins. This inserted ligand binding domain is interactive and was called the I domain in integrins. More recently structural data have shown that an integrin beta-chain also contains an I domain.

Nine of the currently known 18 alpha-chains contain an I domain.This book systematically goes through the current knowledge about these integrins, including the newest additions to the integrin family, the collagen-binding alpha10beta1 and alpha11beta1 integrins. The book discusses ligand binding, signalling properties, knock-out phenotypes and possible involvement in disease. This book comprehensively reviews the current knowledge about I domains in integrins and will serve as a useful reference book for scientists in this field.



Enter the sum





Related Archive Books



Related Books


Comments

Comments for "I Domains in Integrins":


szansadlakobiet.pl

©2009-2015 | DMCA | Contact us